PGT is particularly recommended in cases where genetic risks are high, including:

✔ Prevention of genetic diseases
✔ Identification of causes behind recurrent miscarriages
✔ Selecting the healthiest embryo for implantation

This technique significantly enhances IVF success rates for couples with a family history of genetic conditions.

How and When Should PGS and PGD Be Performed?

PGT is conducted at a specific stage of embryo development. Typically, a biopsy is performed on embryos at the blastocyst stage (day 5-6 of development) in a laboratory setting. A small sample of cells is extracted and analyzed in a genetic laboratory. Results are available within a few days, allowing doctors to select the healthiest embryos for transfer. The timing and application of PGT are tailored to the individual needs of each couple.

What Techniques Are Used in PGT?

PGT utilizes various genetic testing techniques, including:

✔ FISH (Fluorescence In Situ Hybridization): Examines chromosome number and structure.
✔ NGS (Next-Generation Sequencing): Provides comprehensive genetic analysis.
✔ PCR (Polymerase Chain Reaction): Detects single-gene disorders.

The appropriate method is selected based on the couple’s specific medical needs.

Does PGT Harm the Embryo?

The answer is generally no. PGT is one of the most precise techniques in modern reproductive medicine, designed to be performed without harming the embryo. The biopsy sample is taken in a way that does not affect embryo development, and highly trained specialists perform the procedure to minimize risks. PGT is only conducted when necessary and is carefully planned at every stage.

What Diseases Can Be Detected with PGT?

PGT has a wide scope for detecting genetic disorders, including:

✔ Chromosomal abnormalities (e.g., Down syndrome)
✔ Single-gene disorders (e.g., Cystic Fibrosis, Thalassemia, Sickle Cell Anemia)
✔ Hereditary neurological disorders (e.g., Huntington’s Disease, Duchenne Muscular Dystrophy)

By identifying embryos carrying genetic diseases, PGT ensures that only healthy embryos are selected for transfer.

What Are the Advantages of PGT?

PGT provides several key benefits:

✔ Significantly reduces genetic disease risks
✔ Increases IVF success rates
✔ Offers solutions for recurrent miscarriages and failed IVF attempts
✔ Contributes to healthier future generations

PGT is a beacon of hope for couples with genetic risks, providing an essential step toward a successful and healthy pregnancy.